Antibiotic susceptibility testing (AST) specifies effective antibiotic dosage and formulates\na profile of empirical therapy for the proper management of an individual patientâ??s health against\ndeadly infections. Therefore, rapid diagnostic plays a pivotal role in the treatment of bacterial infection.\nIn this article, the authors review the socio-economic burden and emergence of antibiotic resistance.\nAn overview of the phenotypic, genotypic, and emerging techniques for AST has been provided\nand discussed, highlighting the advantages and limitations of each. The historical perspective on\nconventional methods that have paved the way for modern AST like disk diffusion, Epsilometer\ntest (Etest), and microdilution, is presented. Several emerging methods, such as microfluidic-based\noptical and electrochemical AST have been critically evaluated. Finally, the challenges related with\nAST and its outlook in the future are presented.
Loading....